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nosurrender

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Reply with quote  #1 
TEN THOUSAND STEPS!!!!!

 

[4050] A pilot study to increase physical activity in sedentary women at risk for breast cancer.

Korde L, Venzon D, Smith AW, Nehrebecky M, Calhoun T, Sebring N, Drinkard B, Smith M, Prindiville S, Zujewski J, Eng-Wong J. NCI; NIH Clinical Center

Background: Epidemiologic data indicate that physical activity (PA) is associated with a decreased incidence of breast cancer. One study also suggested that physically active breast cancer survivors are at lower risk of recurrence compared with inactive survivors. Thus, PA may be beneficial for both the primary and secondary breast cancer prevention.
Methods: We designed a feasibility study to assess a 12 week PA intervention in women at risk for breast cancer. Eligible women were those at increased risk of breast cancer (by Gail model, family history, atypia on biopsy, or history of Stage 0-III breast cancer). All participants completed a one week baseline PA evaluation. Sedentary women (those with an average daily pedometer step count of <6000 steps per day) were randomized to either PA intervention or control. Intervention group participants received a pedometer, a physician exercise prescription and a motivational/ educational booklet, and were asked to incrementally increase their daily steps to a goal of 10,000 steps per day. Control participants received instruction on daily stretching exercises. The primary objective of the study was to evaluate the feasibility and success of the PA intervention in this population. Secondary objectives included assessing the effect of short-term moderate activity on biomarkers and quality of life. The study was powered to detect a mean increase of 3,000 steps per day in intervention subjects. The Wilcoxon rank sum test was used to evaluate the difference in mean change in step counts between intervention and control participants.
Results: Ninety women were evaluated; of these 45 were at high risk for breast cancer (HR) and 45 were breast cancer survivors (S). The mean age of participants was 54.8 years. The mean baseline step count was 4578 steps per day (SD 2080, range 510 to 9983), and was not significantly different in the two groups (S=4348, HR=4809, p=0.29). Of the 90 participants, 37 (20/45 HR, 17/45 S) were not sedentary and thus not eligible for randomization. The 53 randomized participants had a mean baseline step count of 3190 (SD 1226, range 510-5749). Follow-up step count data were available for 41 participants, (24 intervention, 17 control), of whom 36 completed the 12 week study. The mean increase in step count was 3796 among intervention participants and 2149 among controls (p=0.039). Three intervention participants achieved a final week step count of > 10,000 steps per day.
Conclusion: This moderate intensity intervention was effective in increasing PA in this selected population. Few participants reached the final goal of 10,000 steps per day. Analysis of secondary endpoints is underway. Additional research is needed to determine if this level of PA has an effect on breast cancer related outcomes.


 

 


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purplemb

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Reply with quote  #2 

lol...told you so... na na na


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lizws

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Reply with quote  #3 
To funny! 

Okay - digging out the pedometer.  I meant to this morning but had a late start. blah blah blah blah..........  Walking does work! 

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purplemb

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Reply with quote  #4 
Liz, sometimes talking to you is like talking to my kids...lol.. blah blah blah...lol.. so does yours talk to you ...lol.. love the music... but the alarm thing keeps going off...
hugs my friend..
MB

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lizws

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Reply with quote  #5 
MB - you know I'm just like a kid.  LOL

No mine doesn't talk to me or play music.  DH's does though.  His alarm kept going off also around midnight.  I'll have to ask him how he got it to stop.  Hmmm come to think of it - I haven't seen it for awhile!


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chemoabi

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Reply with quote  #6 
Im wearing mine.  Have along way to go.  Did 4,000 steps today.  Gonna have to give up the computer time in the morning if I want to exercise.
 
Nicki

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Reply with quote  #7 
Gina,

This is very good news.  I read an article that implied that working out only seemed to influence positive results for estrogen positive cancers - I was very discouraged by this.

But my real comment here is before cancer I was a gym rat.  I ran 15-20 miles a week, slim, faaaithfully did my exams, all that "good" stuff.  I think that's why I took it so hard when I was diagnosed with cancer because I thought I was following the "textbook" perfectly.  Not that I was perfect, I drank alcohol, didn't breast feed, etc. etc. so I immediately felt that I was to blame and some how caused this on myself.  I hope this makes some sense to someone  I've beat myself over the head trying to figure out why???? or how????

Sonja   
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