NEW YORK (Reuters Health) Nov 05 - Quantitative Doppler ultrasound vascularity measurements, displayed as 3-dimensional images, contribute considerably to the diagnostic evaluation of suspicious breast lesions, researchers report in the November issue of Radiology.
Dr. Gerald L. LeCarpentier of the University of Michigan, Ann Arbor, and colleagues studied 78 women with palpable or mammographic abnormalities subsequently confirmed by core or excisional biopsies. Forty-six lesions were benign and 32 were malignant.
Thirty-eight patient scans that had been previously partially analyzed were employed as a learning set and 40 new patient scans were used as a test set for previously determined classification indices.
In each patient, a series of color Doppler images had been acquired and reconstructed into a volume encompassing the suspicious mass. Six Doppler vascularity measures were calculated. Radiologist grayscale ratings and the patient's age were also taken into account.
In both the learning and test sets, speed weighted pixel density (SWPD) along with age and grayscale criteria provided significantly superior diagnostic performance than any single index. The 3-variable index was also more accurate than age and grayscale in combination.
The researchers, who note that this index "continues to display promising results," conclude that "SWPD contributes significant independent information."